SCIENCE UNDER AUTOMATION
Rentosertib phase 2a trial
71 patients randomized across four arms for 12 weeks; AI-discovered compound reached clinical testing.
What this result supports
A trial of one compound, not 71 AI drug-discovery trials; safety and efficacy endpoints do not compare AI versus human discovery success.
Evidence record: peer_reviewed. Checked: 2026-10-20.
Where this evidence is used
Drug discovery
- Design an informative clinical study: One AI-origin candidate does not evaluate autonomous trial design.
- Recruit and run a trial: The reported clinical trial is conducted by human clinical teams.
- Assess efficacy and safety: Clinical interpretation remains human; phase 2a is not a discovery-system comparison.